Monday, July 09, 2007

Selective mutism and 22q11.2 deletion syndrome

I found an intriguing Japanese essay Boku no toriatsukai setsumeisho - Mama ha shinmai therapist (An instruction manual of my son - The mother is a novice at therapist).

The writer is a child therapist who have a selectively mute son with 22q11.2 deletion syndrome, a genomic disorder.

I know that there have already been some studies about genomic disorder and selective mutism. The one is about an association with fragile X syndrome and selective mutism [1]. The other is about a deletion of the short arm of chromosome 18 with selectively mute child [2].

But I first hear a child with 22q11.2 deletion syndrome who is colonized by selective mutism.

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[1] Hagerman RJ, Hills J, Scharfenaker S, Lewis H (1999). Fragile X syndrome and selective mutism. American Journal of Medical Genetics. 83(4), 313-317.

[2] Grosso S, Cioni M, Pucci L, Morgese G, Balestri P. (1999). Selective mutism, speech delay, dysmorphisms, and deletion of the short arm of chromosome 18: a distinct entity? Journal of Neurology, Neurosurgery & Psychiatry. 67, 830-831.

Index of SM in Japan